猫和兔胃底灌注期间胃蛋白酶与胃酸分泌之间的相互作用。

Interaction between pepsin and acid secretion during fundic perfusion in cat and rabbit.

Descroix-Vagne M, Perret J P, Daoud-el Baba M, Gros I, Rakotomalala H, Desvigne A, Jourdan G, Nicol P

INSERM U 45, Unité de Physio-Pathologie Digestive, Hôpital E. Herriot, Lyon, France.

Comp Biochem Physiol Comp Physiol. 1993 Feb;104(2):283-6. doi: 10.1016/0300-9629(93)90318-x.

Abstract

The effect of perfusion at pH 5.5 of a Heidenhain pouch on acid and pepsin secretion was studied in cats and rabbits. 2. In basal conditions, acid secretion was not modified by the perfusion while pepsin secretion was increased in both species. 3. After a meal, the perfusion did not modify the stimulation of acid secretion in cats nor the absence of secretions in rabbit. Stimulation of pepsin secretion was the same with or without perfusion in both species. 4. In rabbit, in contrast to cat, pepsin and acid secretions were independent during the meal-induced phase of gastric secretion.

摘要

研究了在pH 5.5条件下对猫和兔的海登海因小胃进行灌注对胃酸和胃蛋白酶分泌的影响。2. 在基础条件下，灌注对胃酸分泌无影响，而在这两个物种中胃蛋白酶分泌均增加。3. 进食后，灌注对猫胃酸分泌的刺激无影响，对兔无分泌情况也无影响。在这两个物种中，无论有无灌注，胃蛋白酶分泌的刺激情况相同。4. 与猫不同，在兔进食诱导的胃分泌阶段，胃蛋白酶和胃酸分泌是相互独立的。