Cangiano G, La Volpe A
CNR International Institute of Genetics and Biophysics, Naples, Italy.
Nucleic Acids Res. 1993 Mar 11;21(5):1133-9. doi: 10.1093/nar/21.5.1133.
We describe the distribution along the chromosomes of Caenorhabditis elegans of two repetitive DNA families, RcS5 and Cerep3 and interstitial telomeric sequences. Both families show, among other interesting features, a preferential location in the terminal 30% of the chromosomes. It is known that in these regions of the genome the frequency of recombination is much higher than in the central portion, genes are rarer and sequences important for chromosome disjunction may lie.
我们描述了秀丽隐杆线虫中两个重复DNA家族RcS5和Cerep3以及间质性端粒序列在染色体上的分布情况。除其他有趣特征外,这两个家族在染色体末端30%区域呈现出优先定位。已知在基因组的这些区域,重组频率远高于中部区域,基因更为稀少,且可能存在对染色体分离很重要的序列。