[人体中甲状腺素（T4）和三碘甲状腺原氨酸（T3）的外周转化]
[Peripheral conversion of T4 and T3 in man].
作者信息
Glöbel B, Berberich R, Oberhausen E
出版信息
Nucl Med (Stuttg). 1975 Jun 30;14(2):106-18.
PMID:809755
Abstract
Our investigations of the peripheral metabolism of T4 and T3 in man demonstrate clearly that T3 is secreted by the thyroid gland and is peripherally formed by conversion from T4. The calculation of the disposal rates indicate furthermore that 40% of the daily metabolised T4 is converted to T3. In this way more than 60% of the daily production of T3 results from peripheral conversion of T4. Our results support the hypothesis that the physiological action of the thyroid hormones is effected mainly by T3.
摘要
我们对人体中甲状腺素（T4）和三碘甲状腺原氨酸（T3）外周代谢的研究清楚地表明，T3由甲状腺分泌，并通过T4在外周转化形成。处置率的计算还表明，每日代谢的T4中有40%转化为T3。这样，每日产生的T3中超过60%来自T4的外周转化。我们的结果支持以下假设：甲状腺激素的生理作用主要由T3实现。
Zotero 插件