Drosophila chromatin: an immunological study.

Antibodies were prepared against chromatin, various chromosomal protein preparations and against cytoplasm from Drosophila larvae. These antibodies were used to study the distribution of antigens in chromatin and chromosomal protein preparations on double diffusion plates. Antisera from all of the mammals tested precipitated both chromatin and DNA on double diffusion plates run in water. This non-specific precipitation was removed by washing in 0.06M NaCL.