营养因素和休息可降低翻身试验阳性初产妇的妊娠高血压和先兆子痫。

Nutritional factors and rest reduce pregnancy-induced hypertension and pre-eclampsia in positive roll-over test primigravidas.

作者信息

Herrera J A

机构信息

Family Health Department, School of Medicine, Universidad del Valle, Cali, Colombia.

出版信息

Int J Gynaecol Obstet. 1993 Apr;41(1):31-5. doi: 10.1016/0020-7292(93)90151-l.

DOI:10.1016/0020-7292(93)90151-l

PMID:8098293

Abstract

OBJECTIVE

The possibility of reducing pregnancy-induced hypertension and preeclampsia in primigravidas with low doses of nutritional factors and relative rest in the left lateral position was investigated in a randomized controlled, double-blind trial.

METHOD

Seventy-four normotensive women at 28-29 weeks' gestation, judged to be at risk of PIH or pre-eclampsia because they presented with a mean blood pressure of 80 mmHg or higher and a positive roll-over test, were studied. The treatment protocol was received by 37 women and the other 37 women received standard antenatal control until delivery.

RESULT

Twenty-nine (78.3%) women in the control group developed PIH and/or pre-eclampsia, as opposed to only 4 (10.8%) cases in the treatment group (P < 0.001). There were no adverse effects of treatment in mothers or in infants.

CONCLUSION

This protocol reduces PIH and pre-eclampsia in primigravidas judged to be at risk of hypertension. Further studies are required to evaluate prostacyclin and prostaglandin E2 changes.

摘要