Herruzo A J, Mozas J, Alarcón J L, López J M, Molina R, Molto L, Martos J
Department of Obstetrics and Gynecology, Virgen de las Nieves Regional Hospital, Granada, Spain.
Int J Gynaecol Obstet. 1993 Apr;41(1):37-41. doi: 10.1016/0020-7292(93)90152-m.
To determine the serum levels of FSH, LH, PRL, estradiol, progesterone and testosterone in umbilical vein blood in a group of normal neonates.
Umbilical vein blood was obtained for serum analyses from 52 newborns (25 females and 27 males) in the Maternity of the Hospital Regional Virgen de las Nieves, Granada (Spain) and means were compared with Student's t-test.
Mean values of prolactin, estradiol and progesterone were similar in both sexes. The levels of gonadotropins in umbilical vein blood found were significantly higher in newborn males than in females (P < 0.001 for LH, P < 0.007 for FSH). Testosterone levels were higher in male neonates than in females (P < 0.004).
Our data reflect the dynamic state of male fetal endocrinological status in comparison to female fetuses, and strongly suggest that the mechanisms of hormonal regulation differ in the two sexes.
测定一组正常新生儿脐静脉血中促卵泡生成素（FSH）、促黄体生成素（LH）、催乳素（PRL）、雌二醇、孕酮和睾酮的血清水平。
从西班牙格拉纳达地区圣母医院妇产科的52例新生儿（25例女性和27例男性）获取脐静脉血进行血清分析，并采用学生t检验比较均值。
两性的催乳素、雌二醇和孕酮均值相似。脐静脉血中促性腺激素水平在新生男婴中显著高于女婴（LH，P < 0.001；FSH，P < 0.007）。男婴的睾酮水平高于女婴（P < 0.004）。
我们的数据反映了与女胎相比男胎内分泌状态的动态情况，并强烈提示两性的激素调节机制不同。
