Gokel J M, Meister P, Hübner G
Virchows Arch A Pathol Anat Histol. 1975 Sep 18;367(4):345-52. doi: 10.1007/BF01239341.
A report is given on a case of proliferative myositis in a 75 year old woman. By fine structural analysis it can be shown, that the characteristic giant cells in proliferative myositis are mesenchymal cells with an intensive protein metabolism. They can be compared to fibroblasts; for a myogenic origin of these cells we found noevidence. Furthermore, various stages in the development and function of the proliferating cells were observed, by which the course of the disease can be expalined.
报告了一名75岁女性的增生性肌炎病例。通过精细结构分析表明,增生性肌炎中特征性的巨细胞是蛋白质代谢活跃的间充质细胞。它们可与成纤维细胞相比较;未发现这些细胞有肌源性起源的证据。此外,观察到了增殖细胞发育和功能的各个阶段,据此可解释疾病的进程。