Ritte U, Neufeld E, Prager E M, Gross M, Hakim I, Khatib A, Bonné-Tamir B
Department of Genetics, Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Israel.
Hum Biol. 1993 Jun;65(3):359-85.
The mitochondrial DNA (mtDNA) of 332 individuals from Israel, including 270 Jews (originating from 7 communities) and 62 Arabs, was analyzed. Each mtDNA haplotype was determined by the fragment patterns of restriction enzymes HpaI, BamHI, HaeII, MspI (HpaII), and AvaII. The variability of the total sample and of each community was high. Of 40 different haplotypes, 20 were found more than once. Most haplotypes are typical of Caucasians, but African types were found among Ethiopian Jews and to a lesser extent among Arabs. The communities differed in their haplotypes: Chi-square tests among six communities showed significant differences for most pairwise comparisons and nonsignificant differences involving mainly the Moroccan Jews. In a genetic distance analysis only the Ethiopian Jews appeared to be distinguished from the other communities. According to a GST analysis, approximately 30% of the variation among the mtDNA restriction maps is attributable to differences between communities.
对来自以色列的332个人的线粒体DNA（mtDNA）进行了分析，其中包括270名犹太人（来自7个社区）和62名阿拉伯人。每个mtDNA单倍型由限制性内切酶HpaI、BamHI、HaeII、MspI（HpaII）和AvaII的片段模式确定。整个样本以及每个社区的变异性都很高。在40种不同的单倍型中，有20种不止出现一次。大多数单倍型是高加索人的典型特征，但在埃塞俄比亚犹太人中发现了非洲类型，在阿拉伯人中也有少量发现。不同社区的单倍型存在差异：六个社区之间的卡方检验显示，大多数两两比较存在显著差异，主要涉及摩洛哥犹太人的比较无显著差异。在遗传距离分析中，只有埃塞俄比亚犹太人似乎与其他社区有所不同。根据GST分析，mtDNA限制性图谱之间约30%的变异可归因于社区之间的差异。
