Naito K, Ishihara M, Senoh Y, Takeda N, Yokoyama N, Iwata S
Department of Otolaryngology, Fujita Health University School of Medicine, Aichi, Japan.
Auris Nasus Larynx. 1993;20(1):31-8. doi: 10.1016/s0385-8146(12)80208-2.
We gave Mao-bushi-saishin-to, a Chinese blended medicine, and azelastine to an adult patient with hay fever due to Japanese cedar pollen and measured nasal resistance and ambient floating pollen counts throughout the time of Japanese cedar pollination in separated years. In the patient Mao-bushi-saishin-to was effective against preseasonal increases in nasal airway resistance but could not control severe episodes of allergic rhinitis caused by high dose exposure to Japanese cedar pollen and also perhaps caused by a priming effect. Azelastine inhibited both pre- and post-seasonal increases in nasal airway resistance but not only on high pollen counts days.
我们给一位因日本柳杉花粉而患花粉症的成年患者服用了汉方混合制剂毛布氏赛新汤和氮卓斯汀，并在不同年份的日本柳杉授粉期间测量了鼻阻力和环境中漂浮的花粉计数。在该患者中，毛布氏赛新汤对季节性前鼻气道阻力增加有效，但无法控制因高剂量接触日本柳杉花粉以及可能由致敏作用引起的严重过敏性鼻炎发作。氮卓斯汀可抑制季节性前和季节性后鼻气道阻力的增加，但不仅在花粉计数高的日子有效。
