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[腹部大手术后早期应用免疫球蛋白治疗。一项随机研究(作者译)]

[Early therapy with immunoglobulins after extensive abdominal operations. A random study (author's transl)].

作者信息

Probst M, Fabian W

出版信息

Langenbecks Arch Chir. 1980;351(2):85-9. doi: 10.1007/BF01237613.

Abstract

A random study with 100 patients was conducted to show whether the immunoglogulin Gamma Venin, when given after rectum extirpation, has an effect on wound healing and other infections. The patients in the test group received 10 g of Gamma Venin within the first 48 h after surgery. The number of days with purulent wound secretion were reduced to 0.71 (test group) as opposed to 7.61 (control) with statistical significance. Primary wound healing was 37% in the test group and 9% in the control group (P < 0.01). Other infections occurred in a similar range. The time of hospitalization was 3.44 days less than in the test group (P < 0.01).

摘要

一项针对100名患者的随机研究旨在表明,直肠切除术后给予免疫球蛋白γ静脉制剂是否对伤口愈合及其他感染有影响。试验组患者在术后48小时内接受10克γ静脉制剂。伤口有脓性分泌物的天数在试验组降至0.71天,而对照组为7.61天,具有统计学意义。试验组一期伤口愈合率为37%,对照组为9%(P<0.01)。其他感染发生率在相似范围内。试验组住院时间比对照组少3.44天(P<0.01)。

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