Monard A, Benoit G, Jacques L, Jardin A
Service de Bactériologie, Hôpital de Bicêtre, Université Paris-Sud.
Prog Urol. 1993 Aug-Sep;3(4):583-9.
Urothelial adhesion of Escherichia coli is one of the principal factors of colonisation and infection of the upper urinary tract. We compared 3 measurements of bacterial adhesion: 1) Mannose-Resistant Haemagglutination (MRHA), é) Adhesion to urothelial cells, 3) Latex particle agglutination, to test 85 strains of Escherichia coli in 42 cases of acute pyelonephritis and 43 cases of acute cystitis. These tests were positive in 73.8% to 85.7% of the acute pyelonephritis population and in 4% to 2.3% of the acute cystitis population (statistically significant difference). This study confirms the major role of strains carrying type PAP adhesion in the pathogenesis of acute pyelonephritis.
大肠杆菌对尿路上皮的黏附是上尿路定植和感染的主要因素之一。我们比较了3种细菌黏附的测量方法:1)抗甘露糖血凝反应(MRHA),2)对尿路上皮细胞的黏附,3)乳胶颗粒凝集,以检测42例急性肾盂肾炎和43例急性膀胱炎患者中的85株大肠杆菌。这些检测在73.8%至85.7%的急性肾盂肾炎患者中呈阳性,而在4%至2.3%的急性膀胱炎患者中呈阳性(差异有统计学意义)。本研究证实了携带PAP型黏附素的菌株在急性肾盂肾炎发病机制中的主要作用。