Birley A J, Barnes B W
Heredity (Edinb). 1975 Aug;35(1):121-6. doi: 10.1038/hdy.1975.73.
Four inbred lines, two homozygous AdhS/S and two homozygous AdhF/F, were extracted from a laboratory cage population of Drosophila melanogaster and crossed in all combinations. Directional dominance for low ADH activity was present and confined to AdhF/S heterozygotes. The remaining genetical differences between the four lines for ADH activity were due to additive genetical variation. The frequency of the AdhS allele in the population was 0-89. The observed directional dominance for low ADH activity in AdhF/S heterozygotes corresponded to the general direction of selection for ADH activity within the population.
从黑腹果蝇的实验室饲养群体中提取了4个近交系，其中2个是纯合的AdhS/S，2个是纯合的AdhF/F，并进行了所有组合的杂交。低ADH活性存在定向显性，且仅限于AdhF/S杂合子。这4个品系在ADH活性上的其余遗传差异是由于加性遗传变异。群体中AdhS等位基因的频率为0.89。在AdhF/S杂合子中观察到的低ADH活性的定向显性与群体内ADH活性的总体选择方向一致。
