强效血管扩张剂2,6 - 二甲基 - 4 - (3 - 硝基苯基) - 1,4 - 二氢吡啶 - 3,5 - 二羧酸3 - [2 - (N - 苄基 - N - 甲基氨基)]乙酯5 - 甲酯盐酸盐（YC - 93）对环磷酸腺苷磷酸二酯酶的抑制作用 - Suppr

Suppr

超能文献

Inhibition of cyclic AMP phosphodiesterase by 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)] ethyl ester 5-methyl ester hydrochloride (YC-93), a potent vasodilator.

作者信息

Sakamoto N, Terai M, Takenaka T, Maeno H

出版信息

Biochem Pharmacol. 1978;27(8):1269-74. doi: 10.1016/0006-2952(78)90462-8.

DOI:10.1016/0006-2952(78)90462-8

PMID:81059

Abstract

摘要

相似文献

Inhibition of cyclic AMP phosphodiesterase by 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)] ethyl ester 5-methyl ester hydrochloride (YC-93), a potent vasodilator.强效血管扩张剂2,6 - 二甲基 - 4 - (3 - 硝基苯基) - 1,4 - 二氢吡啶 - 3,5 - 二羧酸3 - [2 - (N - 苄基 - N - 甲基氨基)]乙酯5 - 甲酯盐酸盐（YC - 93）对环磷酸腺苷磷酸二酯酶的抑制作用

Biochem Pharmacol. 1978;27(8):1269-74. doi: 10.1016/0006-2952(78)90462-8.

Vasodilator profile of a new 1,4-dihydropyridine derivative, 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)]-ethyl ester 5-methyl ester hydrochloride (YC-93).

Arzneimittelforschung. 1976;26(12):2172-8.

Dissociation of cyclic AMP and contractile responses to isoprenaline: effects of a dihydropyridine derivative, nicardipine (YC-93), on canine ventricular muscle.环磷酸腺苷（cAMP）与异丙肾上腺素收缩反应的解离：二氢吡啶衍生物尼卡地平（YC - 93）对犬心室肌的影响

Eur J Pharmacol. 1980 Oct 17;67(2-3):225-33. doi: 10.1016/0014-2999(80)90502-6.

Dihydro- and tetrahydroisoquinolines as inhibitors of cyclic nucleotide phosphodiesterases from dog heart. Structure-activity relationships.二氢和四氢异喹啉作为犬心环核苷酸磷酸二酯酶的抑制剂。构效关系。

Biochem Pharmacol. 1979 Apr 15;28(8):1307-12. doi: 10.1016/0006-2952(79)90430-1.

Trapidil derivatives as potent inhibitors of cyclic AMP phosphodiesterase from heart and coronary arteries.曲匹地尔衍生物作为心脏和冠状动脉中环磷酸腺苷磷酸二酯酶的强效抑制剂。

Biomed Biochim Acta. 1985;44(5):K31-5.

Selective inhibition of cyclic AMP and cyclic GMP phosphodiesterases of cardiac nuclear fraction.心脏细胞核部分环磷酸腺苷和环磷酸鸟苷磷酸二酯酶的选择性抑制作用。

Biochem Pharmacol. 1982 Mar 1;31(5):665-9. doi: 10.1016/0006-2952(82)90447-6.

Determination of a new cerebral vasodilator 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-(N-benzyl-N-methylamino)]-ethyl ester 5-methyl ester hydrochloride (YC-93) in plasma by electron capture gas chromatography.采用电子捕获气相色谱法测定血浆中新型脑血管扩张剂2,6-二甲基-4-(3-硝基苯基)-1,4-二氢吡啶-3,5-二羧酸3-[2-(N-苄基-N-甲基氨基)]-乙酯5-甲酯盐酸盐（YC-93）

J Chromatogr. 1975 Jul 16;110(2):301-7. doi: 10.1016/0021-9673(75)85010-2.

Methylxanthine inhibitors of phosphodiesterases.磷酸二酯酶的甲基黄嘌呤抑制剂。

Methods Enzymol. 1988;159:489-96. doi: 10.1016/0076-6879(88)59048-1.

Effects of 2-nicotinamidethyl nitrate (SG-75), a new antianginal drug, on the cyclic AMP phosphodiesterase activity.新型抗心绞痛药物2-烟酰胺基乙基硝酸盐（SG-75）对环磷酸腺苷磷酸二酯酶活性的影响。

Tohoku J Exp Med. 1980 Feb;130(2):199-201. doi: 10.1620/tjem.130.199.

Inhibition of 3',5'-cyclic nucleotide 3'-phosphohydrolase by a novel 1',2'-cyclic nucleotide.一种新型1',2'-环核苷酸对3',5'-环核苷酸3'-磷酸水解酶的抑制作用

J Cyclic Nucleotide Res. 1982;8(3):181-90.

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Nicardipine releases sustained coronary arterial constriction induced by acetylcholine in the rhesus monkey.

Heart Vessels. 1985 May;1(2):74-7. doi: 10.1007/BF02066352.

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Inhibition of angiotensin II and platelet-derived growth factor-induced vascular smooth muscle cell proliferation by calcium entry blockers.

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