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猫免疫缺陷病毒和马传染性贫血病毒Rev蛋白中的转录后效应结构域。

Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus.

作者信息

Mancuso V A, Hope T J, Zhu L, Derse D, Phillips T, Parslow T G

机构信息

Department of Pathology, University of California, San Francisco 94143-0506.

出版信息

J Virol. 1994 Mar;68(3):1998-2001. doi: 10.1128/JVI.68.3.1998-2001.1994.

DOI:10.1128/JVI.68.3.1998-2001.1994
PMID:8107262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC236666/
Abstract

By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.

摘要

通过系统地剖析猫免疫缺陷病毒（FIV）和马传染性贫血病毒（EIAV）的Rev蛋白，我们在每种病毒中都鉴定出了一个短肽，该短肽在功能上可与其他逆转录病毒的Rev样蛋白中的效应结构域互换。FIV和EIAV的活性序列在几个方面与其他已知效应物不同，可能代表了一类独特的效应结构域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f39/236666/142f029d1982/jvirol00012-0748-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f39/236666/1da882c39977/jvirol00012-0747-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f39/236666/5496a7025f43/jvirol00012-0747-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f39/236666/142f029d1982/jvirol00012-0748-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f39/236666/1da882c39977/jvirol00012-0747-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f39/236666/5496a7025f43/jvirol00012-0747-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f39/236666/142f029d1982/jvirol00012-0748-a.jpg

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The molecular biology of feline immunodeficiency virus (FIV).猫免疫缺陷病毒（FIV）的分子生物学。
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本文引用的文献

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Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein.人嗜T淋巴细胞病毒1型（HTLV-1）的rex蛋白对人免疫缺陷病毒1型（HIV-1）rev蛋白的功能替代
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Characterization of functional domains of equine infectious anemia virus Rev suggests a bipartite RNA-binding domain.马传染性贫血病毒Rev功能域的表征表明存在一个二分RNA结合域。
J Virol. 2006 Apr;80(8):3844-52. doi: 10.1128/JVI.80.8.3844-3852.2006.
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