Clark E A, Ledbetter J A
Department of Microbiology, University of Washington Medical Center, Seattle 98195.
Nature. 1994 Feb 3;367(6462):425-8. doi: 10.1038/367425a0.
The B cells of the immune system, which secrete antibodies against foreign antigens, are fully specific and effective only after maturation in lymph nodes and other lymphoid tissues. Immunocompetent T cells play a crucial part in this process, but the molecular details of the way in which the two cell types interact have only recently become apparent.
免疫系统中的B细胞能够分泌针对外来抗原的抗体，只有在淋巴结和其他淋巴组织中成熟后才具有完全的特异性和有效性。具有免疫活性的T细胞在这一过程中发挥着关键作用，但这两种细胞类型相互作用方式的分子细节直到最近才变得清晰。
