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外周静脉浸润性坏死

Peripheral intravenous infiltration necrosis.

作者信息

Yosowitz P, Ekland D A, Shaw R C, Parsons R W

出版信息

Ann Surg. 1975 Nov;182(5):553-6. doi: 10.1097/00000658-197511000-00003.

DOI:10.1097/00000658-197511000-00003
PMID:811181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1344036/
Abstract

Peripheral extravasation of intravenous solutions containing calcium salts and/or 10% dextrose has caused significant local tissue necrosis in 8 patients, including 6 infants. These incidents prolonged hospitalization and in 5 cases caused severe disfigurement or imperiled limb function. Treatment followed established principles of debridement, early skin grafting and secondary reconstruction as needed. While intravenous alimentation or the administration of calcium salts if often indicated by the clinical situation, the physician administering these drugs must realize that extravasation may cause serious sequelae.

摘要

含有钙盐和/或10%葡萄糖的静脉溶液外周渗漏已导致8例患者出现严重局部组织坏死，其中包括6例婴儿。这些事件延长了住院时间，5例导致严重毁容或危及肢体功能。治疗遵循既定的清创、早期植皮及必要时二期重建原则。虽然临床情况常表明需要静脉营养或给予钙盐，但使用这些药物的医生必须认识到渗漏可能会导致严重后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/8873f835d7e9/annsurg00285-0028-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/54bba96ee27b/annsurg00285-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/9ec786696df2/annsurg00285-0026-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/a61ffdac87a3/annsurg00285-0026-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/4c2888267d0b/annsurg00285-0026-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/b3fbf28d954f/annsurg00285-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/0c07b328f70c/annsurg00285-0027-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/09f3d7cdd1e3/annsurg00285-0027-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/ecb530cad2e6/annsurg00285-0028-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/8873f835d7e9/annsurg00285-0028-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/54bba96ee27b/annsurg00285-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/9ec786696df2/annsurg00285-0026-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/a61ffdac87a3/annsurg00285-0026-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/4c2888267d0b/annsurg00285-0026-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/b3fbf28d954f/annsurg00285-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/0c07b328f70c/annsurg00285-0027-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/09f3d7cdd1e3/annsurg00285-0027-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/ecb530cad2e6/annsurg00285-0028-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9654/1344036/8873f835d7e9/annsurg00285-0028-b.jpg

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Peripheral intravenous infiltration necrosis.外周静脉浸润性坏死
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Gastric Necrosis because of Ingestion of Calcium Chloride.因摄入氯化钙导致的胃坏死。
ACG Case Rep J. 2020 Aug 20;7(8):e00446. doi: 10.14309/crj.0000000000000446. eCollection 2020 Aug.
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Outcomes and Management of Peripheral Intravenous Infiltration Injuries.

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Treatment of noradrenaline infusion necrosis.去甲肾上腺素输注性坏死的治疗。
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Hand (N Y). 2022 Jan;17(1):148-154. doi: 10.1177/1558944720906494. Epub 2020 Feb 28.
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A Case of Metronidazole Injection Infiltration Without Sequelae.甲硝唑注射液渗漏无后遗症一例。
Hosp Pharm. 2017 Sep;52(8):559-563. doi: 10.1177/0018578717722885. Epub 2017 Aug 4.
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Incidence and Severity of Prescribing Errors in Parenteral Nutrition for Pediatric Inpatients at a Neonatal and Pediatric Intensive Care Unit.新生儿及儿科重症监护病房儿科住院患者肠外营养处方错误的发生率及严重程度
Front Pediatr. 2017 Jun 30;5:149. doi: 10.3389/fped.2017.00149. eCollection 2017.
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Identification of Risk Factors for Intravenous Infiltration among Hospitalized Children: A Retrospective Study.住院儿童静脉输液渗漏危险因素的识别：一项回顾性研究
PLoS One. 2016 Jun 28;11(6):e0158045. doi: 10.1371/journal.pone.0158045. eCollection 2016.
7
Bullous Dermatitis and Skin Necrosis Developing after Adrenalin Extravasation.肾上腺素外渗后发生的大疱性皮炎和皮肤坏死
Eurasian J Med. 2015 Oct;47(3):226-8. doi: 10.5152/eurasianjmed.2015.58.
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Management of the extravasation of anti-neoplastic agents.抗肿瘤药物外渗的处理
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