Chen J W
Changhai Hospital, Shanghai.
Zhonghua Wai Ke Za Zhi. 1993 May;31(5):312-4.
The effect of Rhizoma Ligustici Chuanxiong and allopurinol on ischemia-reperfusion damage of rabbit ear flap was studied. The results showed that MDA level was higher and SOD activity lower distinctly at 0.5 hour after reperfusion than that at 16 hours of postischemia and preischemia, Rhizoma Ligustici Chuanxiong and allopurinol changed the result markedly with a decrease of necrosis rate. The effect of Rhizoma Ligustici Chuanxiong was more significant than that of allopurinol in promoting microcirculation, preventing clot formation, reducing exudation and hemorrhage.
研究了川芎和别嘌醇对兔耳皮瓣缺血再灌注损伤的影响。结果显示，再灌注0.5小时时丙二醛（MDA）水平明显高于缺血16小时及缺血前，超氧化物歧化酶（SOD）活性明显低于缺血16小时及缺血前，川芎和别嘌醇显著改变了这一结果，坏死率降低。川芎在促进微循环、防止血栓形成、减少渗出和出血方面的作用比别嘌醇更显著。
