Digiacomo R F, Gale J L, Wang S P, Kiviat M D
Br J Vener Dis. 1975 Oct;51(5):310-3. doi: 10.1136/sti.51.5.310.
Two adult male baboons (Papio cynocephalus) were infected by urethral catheter with a Type D strain of Chlamydia trachomatis isolated from a male patient with nongonococcal urethritis. Chlamydial organisms were shed from the urethra for about 90 days and serum antibody developed. Intraurethral re-inoculation of homologous and heterologous (Type I) strains of Chalmydia, 4 and 11 months later, resulted in relatively shorter periods of infection of less than 15 days. The antibody titres and type-specific patterns were not substantially influenced by re-infection.
两只成年雄性狒狒(豚尾狒狒)通过尿道导管感染了从一名患有非淋菌性尿道炎的男性患者分离出的沙眼衣原体D型菌株。衣原体微生物从尿道排出约90天,并产生了血清抗体。4个月和11个月后,对同源和异源(I型)沙眼衣原体菌株进行尿道内再次接种,导致感染期相对较短,不到15天。再次感染对抗体滴度和型特异性模式没有实质性影响。