Duncan I W, Kaufman T C
Genetics. 1975 Aug;80(4):733-52. doi: 10.1093/genetics/80.4.733.
In order to define more precisely the most proximal portion of chromosome 3R in Drosophila melanogaster, several new chromosome aberrations involving this region have been recovered and analyzed. These new arrangements were recovered as induced reversions of two dominant mutations, ANTPNs and dsxD, located in the region of interest. The results of the analysis have allowed the localization of several existing mutations, have further elucidated the complex homoeotic locus which resides in this region, and have confirmed the efficacy of this type of screen in the analysis of specific chromosome regions.
为了更精确地界定黑腹果蝇3R染色体最近端的部分,已获得并分析了几个涉及该区域的新染色体畸变。这些新的排列是作为位于感兴趣区域的两个显性突变ANTPNs和dsxD的诱导回复突变而获得的。分析结果已确定了几个现有突变的位置,进一步阐明了位于该区域的复杂同源异型基因座,并证实了这种筛选类型在分析特定染色体区域方面的有效性。