Sugiyama E, Honda K, Katsuyama Y, Uchiyama S, Tsuchikane A, Ota M, Fukushima H
Department of Legal Medicine, Shinshu University School of Medicine, Nagano, Japan.
Int J Legal Med. 1993;106(3):111-4. doi: 10.1007/BF01225228.
Population studies among Japanese were carried out at the D1S80 locus by the polymerase chain reaction and subsequent analysis in agarose gel electrophoresis. A total of 58 genotypes and 25 alleles ranging from 16 to 45 repeat units were observed in a population group of 121 unrelated individuals. The alleles with 18, 24 and 30 repeat units were found to be most common. Some large alleles with more than 42 repeat units were first observed in this study. Statistical tests for Hardy-Weinberg equilibrium showed that no significant deviations could be found in this Japanese population sample. The values of the mean exclusion chance and the discriminating power (DP) were calculated to be 0.76 and 0.91, respectively. The observed heterozygosity was 0.91.
通过聚合酶链反应及随后的琼脂糖凝胶电泳分析，对日本人群在D1S80基因座进行了群体研究。在一个由121名无亲缘关系个体组成的群体中，共观察到58种基因型和25个等位基因，重复单位数量从16到45个不等。发现重复单位为18、24和30的等位基因最为常见。本研究首次观察到一些重复单位超过42个的大等位基因。哈迪-温伯格平衡的统计检验表明，在这个日本人群样本中未发现显著偏差。平均排除机会和鉴别力（DP）的值分别计算为0.76和0.91。观察到的杂合度为0.91。
