Bolotova E N, Sergeev P V, Shimanovskiĭ N L, Kerimaliev M K
Biull Eksp Biol Med. 1993 Sep;116(9):277-9.
It has been studied in vivo and vitro effects of and NMR contrast media on renal lipid peroxidation in intact rats and animals with experimental pathologies; glycerine nephritis and CCL4 intoxication. The effects of contrast media was dependent on the time of application, their concentration and conditions of elimination organs. The value of contrast media effect was decreased in order: GdCl3, bilignost, triombrast, iogexol, omnipaque. Gd-DTPA did not influence lipid peroxidation in any cases.
已经研究了体内和体外NMR造影剂对完整大鼠以及患有实验性病变(甘油性肾炎和四氯化碳中毒)动物的肾脏脂质过氧化的影响。造影剂的作用取决于应用时间、其浓度以及排泄器官的状况。造影剂作用的大小依次降低:氯化钆、双香豆素、三溴沙仑、碘克沙醇、欧乃派克。钆喷酸葡胺在任何情况下均不影响脂质过氧化。