Nazarenko M E, Shtrygol' S Iu, Slobodin V B
Departments of Pharmacology and General, Organic, and Bioorganic Chemistry, Ivanovo State Medical Academy, Ivanovo, 153462 Russia.
Eksp Klin Farmakol. 2003 Nov-Dec;66(6):29-31.
Bilobil, a commercial preparation based on Ginkgo biloba extract, improves the functional state of kidney and increases the survival of rats with glycerol-induced acute renal insufficiency. One possible mechanism of this effect is related to the ability of bilobil to simulate the renal antioxidant system, thus decreasing the rate of lipid peroxidation processes and reducing the renal damage. The results show good prospects for the use of bilobil in nephrology.
必洛比(Bilobil)是一种基于银杏叶提取物的商业制剂,可改善肾脏功能状态,并提高甘油诱导的急性肾功能不全大鼠的存活率。这种作用的一种可能机制与必洛比模拟肾脏抗氧化系统的能力有关,从而降低脂质过氧化过程的速率并减轻肾脏损伤。结果表明必洛比在肾脏病学中的应用前景良好。