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[胆囊胆总管结石的腹腔镜胆囊切除术。“治疗性分离”还是传统手术方法?]

[Laparoscopic cholecystectomy in cholecysto-choledocholithiasis. "Therapeutic splitting" or conventional surgical procedure?].

作者信息

Sungler P, Heinerman P M, Mayer F, Boeckl O

机构信息

Chirurgische Abteilung, Ludwig-Boltzmann-Institut für experimentelle und gastroenterologische Chirurgie.

出版信息

Chirurg. 1993 Dec;64(12):1012-5; discussion 1016-7.

PMID:8119085
Abstract

In a prospective study the impact of preoperative, selective endoscopic cholangiography (ERC/P) and therapy was evaluated in 586 consecutive patients with symptomatic gallstone disease in respect of biliary pathology and laparoscopic cholecystectomy (n = 520). Exclusion criteria for the admission to the study were previous gastric surgery, necrotizing cholecystitis and gallbladder perforation. Because of presumed pathology on ultrasound, suggestive for common bile duct stones or papillary stenosis 59 patients (11.3%) had preoperative ERC/P. In all patients with calculi (n = 40) endoscopic stone removal was successfully performed with/without sphincterotomy (EPT), in three cases of clinically relevant stenosis EPT was indicated. Morbidity was 1.6% after ERC/EPT, in the endoscopic group operative morbidity and mortality was zero. In the non-endoscopic group (n = 461) sixteen complications occurred, although none could have been avoided by preoperative cholangiography. Two patients showed retained calculi (0.3%), missed by preoperative diagnostics. Both cases were successfully treated by ERC. Intraoperative cholangiograms were not done routinely (11%). In conclusion, we think, that selective, preoperative ERC/P, EPT and stone removal--if necessary--facilitate a very low morbidity and mortality in the laparoscopic treatment of complicated gallstone disease. By means of the "therapeutical splitting" the conversion to open bile duct surgery with all its higher morbidity and mortality can be eradicated. Also, only a few of the endoscopically operating hospitals already provide equipment for laparoscopic bile duct revision, not to talk about the gifted and experienced surgeons.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在一项前瞻性研究中,针对586例连续性有症状胆结石疾病患者(其中520例行腹腔镜胆囊切除术),就胆道病理情况评估了术前选择性内镜逆行胰胆管造影(ERC/P)及其治疗的影响。该研究的排除标准为既往有胃部手术史、坏死性胆囊炎和胆囊穿孔。由于超声检查推测存在病理情况,提示胆总管结石或乳头狭窄,59例患者(11.3%)接受了术前ERC/P。所有结石患者(n = 40)均成功进行了内镜下取石,伴或不伴括约肌切开术(EPT),3例临床相关狭窄患者接受了EPT治疗。ERC/EPT后的发病率为1.6%,内镜组的手术发病率和死亡率为零。在非内镜组(n = 461)中发生了16例并发症,尽管术前胆管造影无法避免任何并发症。2例患者出现残留结石(0.3%),术前诊断遗漏。这两例均通过ERC成功治疗。术中胆管造影未常规进行(11%)。总之,我们认为,选择性术前ERC/P、EPT及必要时的取石术,可使复杂胆结石疾病的腹腔镜治疗发病率和死亡率极低。通过“治疗性区分”,可消除转为开腹胆管手术带来的更高发病率和死亡率。此外,只有少数内镜手术医院已配备腹腔镜胆管修复设备,更不用说有资质且经验丰富的外科医生了。(摘要截断于250字)

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