Saint R, Patterson B
Department of Biochemistry, University of Adelaide, Australia.
Genetica. 1993;90(2-3):157-63. doi: 10.1007/BF01435037.
The zygotic expression of only a few Drosophila genes is known to be required for completion of the normal embryonic mitoses. Molecular genetic analyses of these genes reveal that they fall into two classes, those whose mRNA levels are regulated in a stage and/or tissue-specific fashion to control cell cycle events during embryogenesis, and those in which, in the absence of functional zygotic expression, the maternal mRNA contribution does not provide sufficient product to complete the normal embryonic mitoses. Genes that comprise the first class are involved in the developmental control of the cell cycle, while those of the second class identify components of the cell cycle machinery.
已知仅少数果蝇基因的合子表达是正常胚胎有丝分裂完成所必需的。对这些基因的分子遗传学分析表明，它们可分为两类，一类基因的mRNA水平以阶段和/或组织特异性方式受到调控，以控制胚胎发育过程中的细胞周期事件；另一类基因在缺乏功能性合子表达时，母体mRNA的贡献不足以提供足够的产物来完成正常的胚胎有丝分裂。属于第一类的基因参与细胞周期的发育控制，而第二类基因则确定细胞周期机制的组成部分。
