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氧自由基与急性胰腺炎:事实还是虚构?

Oxygen free radicals and acute pancreatitis: fact or fiction?

作者信息

Creagh T A, Leahy A L, Bouchier-Hayes D J, Tormey W, Leader M, Broe P J

机构信息

Department of Surgery, Beaumont Hospital, Dublin, Ireland.

出版信息

Ir J Med Sci. 1993 Dec;162(12):497-8. doi: 10.1007/BF03022581.

Abstract

The effect of oxygen free radical suppression was studied in the taurocholate model of acute pancreatitis in the rat using systemic allopurinol, superoxide dismutase (S.O.D.) and catalase. None of the treatments were beneficial which suggests that oxygen free radical suppression is unlikely to be clinically beneficial in acute pancreatitis.

摘要

使用全身应用别嘌呤醇、超氧化物歧化酶(S.O.D.)和过氧化氢酶,在大鼠牛磺胆酸盐急性胰腺炎模型中研究了氧自由基抑制的作用。这些治疗均无益处,这表明在急性胰腺炎中抑制氧自由基不太可能具有临床益处。

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