Sukhorukova N L, Gukasian L A, Cherkasova V V, Korzhenkova M P
Zh Mikrobiol Epidemiol Immunobiol. 1975 Aug(8):25-30.
It was shown in the passive hemagglutination test (PHAT) with a type-specific somatic antigen on 147 carriers of toxigenic diphtheria bacilli that the PHAT titres of 1/80 and over were determined in 64% of bacteria. In the process of carrier state of toxigenic bacteria antimicrobial antibodies were detected in 79% of the children; after the release from the carrier state, the percentage was from 57 to 26, depending on the time lapse after it. Among the carriers of nontoxigenic diphtheria bacilli the PHAT titre of 1/80 and over was established in up to 20% of children, and only in those which were in the focus of toxigenic bacilli carriers. The applied test could be used for epidemiological purpose to determine the spread of the carrier state of toxigenic bacteria in a collective body.
在用型特异性菌体抗原对白喉产毒杆菌的147名带菌者进行的被动血凝试验（PHAT）中发现，64%的细菌其PHAT效价为1/80及以上。在产毒细菌的带菌状态过程中，79%的儿童检测到抗菌抗体；从带菌状态解除后，该百分比根据解除后经过的时间从57%降至26%。在无毒白喉杆菌带菌者中，高达20%的儿童其PHAT效价为1/80及以上，且仅在那些处于产毒杆菌带菌者疫源地的儿童中。所应用的试验可用于流行病学目的，以确定产毒细菌带菌状态在集体人群中的传播情况。
