Kattan S, Husain I, el-Faqih S R, Atassi R
Department of Surgery, College of Medicine, Riyadh, Saudi Arabia.
J Endourol. 1993 Dec;7(6):449-51. doi: 10.1089/end.1993.7.449.
In a prospective pilot study, 26 patients with non-infection-related renal or ureteric stones and sterile urine were examined for evidence of bacteriuria and bacteremia following extracorporeal shock wave lithotripsy (SWL). Blood samples were obtained for aerobic and anaerobic bacterial culture at the end of, and 1 hour after, the SWL procedure. Urine cultures were performed 24 hours before and after treatment. Bacteremia was recorded in 7.7% of the patients immediately after SWL but in no patient at 1 hour after treatment. None of the patients manifested significant bacteriuria or post-SWL fever. These findings support the contention that, provided the urine is sterile and a negative history of urosepsis is available, antibiotic prophylaxis is unnecessary in patients with non-infected renal stones submitted to SWL treatment.
在一项前瞻性试点研究中,对26例患有非感染相关肾或输尿管结石且尿液无菌的患者进行了体外冲击波碎石术(SWL)后菌尿和菌血症证据的检查。在SWL手术结束时和术后1小时采集血样进行需氧和厌氧细菌培养。在治疗前后24小时进行尿培养。SWL术后立即有7.7%的患者出现菌血症,但治疗后1小时无患者出现菌血症。所有患者均未出现明显菌尿或SWL术后发热。这些发现支持了这样的观点,即如果尿液无菌且有尿路败血症阴性病史,接受SWL治疗的非感染性肾结石患者无需预防性使用抗生素。