Whitson B, Campbell G D
Department of Medicine, Louisiana State University, Shreveport.
Geriatrics. 1994 Mar;49(3):24-6, 31-6.
Pneumonia is a common and important infectious disease in all age groups but especially in the elderly. Mortality and morbidity are quite high when associated with certain risk factors such as comorbid medical conditions and clinical features that implicate more severe disease. In the absence of such features, patients can be treated quite safely out of the hospital, as long as followup and compliance issues are not a problem. Therapy should be directed toward gram-positive and gram-negative aerobic bacteria and, at times, be further expanded to cover atypical organisms such as Legionella sp. Appropriate antimicrobial agents are those that not only cover expected microorganisms but are compatible with each patient's existing medical regimen.
肺炎是各年龄组中常见且重要的传染病,在老年人中尤为如此。当与某些风险因素相关时,如合并症和提示病情更严重的临床特征,死亡率和发病率相当高。在没有这些特征的情况下,只要随访和依从性问题不存在,患者可以在院外得到相当安全的治疗。治疗应针对革兰氏阳性和革兰氏阴性需氧菌,有时还应进一步扩大覆盖范围,以包括非典型病原体,如军团菌属。合适的抗菌药物不仅要覆盖预期的微生物,还要与每位患者现有的医疗方案相兼容。