小鼠IgG2a免疫球蛋白一级结构的测定。轻链的氨基酸序列。
Determination of the primary structure of a mouse IgG2a immunoglobulin. Amino-acid sequence of the light chain.
作者信息
Schiff C, Fougereau M
出版信息
Eur J Biochem. 1975 Nov 15;59(2):525-37. doi: 10.1111/j.1432-1033.1975.tb02479.x.
Abstract
The amino acid sequence of the light chain of the mouse monoclonal MOPC 173 immunoglobulin molecule (IgG2a,chi) is presented. This kappa chain contains 214 residues. Comparisons of this sequence with murine kappa chains already published by other workers bring a confirmation of the large size of the murine V chi chain pool. A complete identity was found with the constant region of the light chain of MOPC 21 from residue 97 to residue 214.
摘要
本文展示了小鼠单克隆MOPC 173免疫球蛋白分子（IgG2a，κ）轻链的氨基酸序列。该κ链包含214个残基。将此序列与其他研究者已发表的小鼠κ链进行比较，证实了小鼠Vκ链库的规模较大。从第97位残基到第214位残基，发现它与MOPC 21轻链的恒定区完全相同。
Zotero 插件