Suppr超能文献

[接种乙型肝炎疫苗后发生的急性脊髓炎]

[Acute myelitis after vaccination against hepatitis B].

作者信息

Mahassin F, Algayres J P, Valmary J, Bili H, Coutant G, Bequet D, Daly J P

机构信息

Service de Clinique médicale, Hôpital d'Instruction des Armées du Val-de-Grâce, Paris.

出版信息

Presse Med. 1993 Dec 18;22(40):1997-8.

PMID:8127802
Abstract

A 56-year old man was hospitalized for spasmodic paraparesis with sphincter disorders. After exclusion of spinal cord compression and all other inflammatory, infectious or neoplastic causes, the possibility of a connexion with an hepatitis B vaccination performed with a recumbent vaccine three weeks before the neurological disorders appeared was considered. The pathogenesis of such a myelitis remains uncertain. It is based on the possible reactivation of a dormant virus or a crossed antigenic reaction between a protein of the vaccine and the nervous system. The course of the disease is usually favourable. The frequency of this complication would be more accurately determined if all neurological manifestations occurring after hepatitis B vaccination were reported.

摘要

一名56岁男性因痉挛性截瘫伴括约肌功能障碍入院。在排除脊髓压迫及所有其他炎症、感染或肿瘤性病因后,考虑到在神经功能障碍出现前三周接种了重组疫苗进行乙肝疫苗接种,有可能与之相关。这种脊髓炎的发病机制尚不确定。其依据可能是潜伏病毒的重新激活或疫苗蛋白与神经系统之间的交叉抗原反应。该病病程通常良好。如果报告所有乙肝疫苗接种后出现的神经学表现,这种并发症的发生率将能更准确地确定。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验