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炎症性肠病中与皮质类固醇撤药相关的假性脑瘤

Pseudotumor cerebri associated with corticosteroid withdrawal in inflammatory bowel disease.

作者信息

Liu G T, Kay M D, Bienfang D C, Schatz N J

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida.

出版信息

Am J Ophthalmol. 1994 Mar 15;117(3):352-7. doi: 10.1016/s0002-9394(14)73145-9.

DOI:10.1016/s0002-9394(14)73145-9
PMID:8129010
Abstract

We treated two patients with Crohn's disease and one patient with ulcerative colitis who developed headache, papilledema, and intracranial hypertension (pseudotumor cerebri) during corticosteroid withdrawal. One had four separate episodes with corticosteroid withdrawal, which suggested a causal relationship. This association between pseudotumor cerebri and corticosteroid withdrawal has been documented in children, but is rare in adults with inflammatory bowel disease.

摘要

我们治疗了两名克罗恩病患者和一名溃疡性结肠炎患者,他们在停用皮质类固醇期间出现了头痛、视乳头水肿和颅内高压(假性脑瘤)。其中一名患者在停用皮质类固醇时有四次不同发作,提示存在因果关系。假性脑瘤与停用皮质类固醇之间的这种关联在儿童中已有记载,但在患有炎症性肠病的成人中很少见。

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