Smith E A, Kilpatrick E S
Department of Anaesthesia, Western Infirmary, Glasgow, Scotland, UK.
Anaesthesia. 1994 Feb;49(2):129-32. doi: 10.1111/j.1365-2044.1994.tb03369.x.
Variations in haematocrit are known to affect the accuracy of reagent strip tests for glucose. We have investigated 10 patients during cardiopulmonary bypass, where intra-operative decreases in haematocrit occur. Whole blood glucose concentrations were measured on five occasions at 30 min intervals during the procedure using the Glucometer II, One Touch II and Reflolux II meters as well as a reference instrument (YSI Model 23 AM). Haematocrits were recorded simultaneously. Overall, for every 10% fall in haematocrit, Glucometer II measurements rose by 22% (r = 0.74, p < 0.00001), One Touch II measurements fell by 3% (r = 0.44, p < 0.002) and the Reflolux II measurements showed no significant variation. The One Touch II showed closer agreement to the reference (mean bias 0.3 mmol.l-1 (95% between +0.86 and -0.26)) than the Reflolux II (bias 1.58 (+3.40 to -0.24)) or the Glucometer II (bias 3.25 (+6.18 to 0.32)). Thus, depending on the meter used, spuriously large intraoperative changes in blood glucose may seem to arise where patient haematocrit varies.
已知血细胞比容的变化会影响血糖试纸条检测的准确性。我们对10例接受体外循环手术的患者进行了研究，这些患者术中血细胞比容会降低。在手术过程中，每隔30分钟使用血糖仪II、One Touch II和Reflolux II血糖仪以及一台参考仪器（YSI 23 AM型）测量5次全血葡萄糖浓度。同时记录血细胞比容。总体而言，血细胞比容每下降10%，血糖仪II的测量值上升22%（r = 0.74，p < 0.00001），One Touch II的测量值下降3%（r = 0.44，p < 0.002），而Reflolux II的测量值无显著变化。与Reflolux II（偏差1.
