Molenaar P C, Boomsma D I, Dolan C V
University of Amsterdam, Department of Psychology, The Netherlands.
Behav Genet. 1993 Nov;23(6):519-24. doi: 10.1007/BF01068142.
An illustrative list is presented of human and animal studies which each point to the existence of a third source, in addition to genetic and environmental factors, underlying phenotypic differences in development. It is argued that this third source may consist of nonlinear epigenetic processes that can create variability at all phenotypical-somatic and behavioral-levels. In a quantitative genetic analysis with human subjects, these processes are confounded with within-family environmental influences. A preliminary model to quantify these influences is introduced.
本文列出了一系列具有代表性的人类和动物研究，这些研究均指出，除了遗传和环境因素外，发育过程中的表型差异还存在第三个潜在来源。有人认为，这第三个来源可能由非线性表观遗传过程组成，这些过程可在所有表型-躯体和行为水平上产生变异性。在一项针对人类受试者的数量遗传学分析中，这些过程与家庭内部环境影响相互混淆。本文介绍了一个量化这些影响的初步模型。
