Moshkowitz M, Gorea A, Arber N, Konikoff F, Berger S, Gilat T
Department of Gastroenterology, Ichilov Hospital, Tel-Aviv Medical Center, Israel.
J Clin Pathol. 1994 Feb;47(2):172-4. doi: 10.1136/jcp.47.2.172.
The survival of clinical isolates of H pylori at two cultural ages (two and four days) at pH 2, in the presence of different buffers, with and without urea, was investigated. It was found that the morphological changes which occur with longer incubation of H pylori have an inverse correlation with its resistance to an acidic environment. The finding that the addition of urea almost reversed this phenomenon and prolonged survival of the cultures emphasises the role of urea in the survival of H pylori in acidic environments.
研究了幽门螺杆菌临床分离株在两种培养时间（两天和四天）、pH值为2、存在不同缓冲液、有或无尿素的情况下的存活情况。发现幽门螺杆菌培养时间延长时发生的形态变化与其对酸性环境的抗性呈负相关。添加尿素几乎逆转了这一现象并延长了培养物的存活时间，这一发现强调了尿素在幽门螺杆菌在酸性环境中存活的作用。
