从孟加拉国霍乱样疾病患者中分离出的霍乱弧菌O139（同义词：孟加拉型）的特性分析。

Characterization of Vibrio cholerae O139 synonym Bengal isolated from patients with cholera-like disease in Bangladesh.

作者信息

Higa N, Honma Y, Albert M J, Iwanaga M

机构信息

Department of Bacteriology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.

出版信息

Microbiol Immunol. 1993;37(12):971-4. doi: 10.1111/j.1348-0421.1993.tb01731.x.

DOI:10.1111/j.1348-0421.1993.tb01731.x

PMID:8133802

Abstract

Vibrio cholerae O139 (synonym Bengal), a novel serovar of V. cholerae, is the causative agent of large outbreaks of cholera-like illness currently sweeping India and Bangladesh. Eight randomly selected V. cholerae O139 isolates were studied for their biological properties, which were compared with those of V. cholerae O1 and other V. cholerae non-O1. The V. cholerae O139 isolates were characterized by the production of large amount of cholera toxin, hemagglutination, weak hemolytic properties, resistance to polymyxin B, lysogeny with, and production of, kappa type phage (4/8 isolates only), and resistance to both classical and El Tor-specific phages. Thus, V. cholerae O139 isolates had an overall similarity with V. cholerae O1 El Tor.

摘要

霍乱弧菌O139（同义词孟加拉型）是霍乱弧菌的一种新型血清型，是目前席卷印度和孟加拉国的大规模霍乱样疾病暴发的病原体。对随机选取的8株霍乱弧菌O139分离株的生物学特性进行了研究，并与霍乱弧菌O1和其他霍乱弧菌非O1的生物学特性进行了比较。霍乱弧菌O139分离株的特点是产生大量霍乱毒素、具有血凝性、溶血特性较弱、对多粘菌素B耐药、可被κ型噬菌体溶原化并产生κ型噬菌体（仅4/8分离株），以及对经典和埃尔托型特异性噬菌体均耐药。因此，霍乱弧菌O139分离株与霍乱弧菌O1埃尔托型总体相似。