Bartolozzi C, Lencioni R, Caramella D, Falaschi F, Cioni R, DiCoscio G
Department of Radiology, University of Pisa, Italy.
Radiology. 1994 Apr;191(1):123-8. doi: 10.1148/radiology.191.1.8134557.
To investigate the reliability of computed tomography (CT) and magnetic resonance (MR) imaging in the evaluation of the response of hepatocellular carcinoma (HCC) to transcatheter arterial embolization (TAE) followed by percutaneous ethanol injection (PEI).
Between January 1991 and November 1992, 20 patients (15 men and five women, aged 53-73 years [mean, 64.6 years]) with 31 HCC lesions underwent CT and MR imaging before and after treatment with combined TAE and PEI.
Twenty-seven tumors, which were hypointense on post-treatment T2-weighted images and on gadolinium-enhanced T1-weighted images, were seen to be necrotic at biopsy. In four cases of incomplete necrosis, viable tumor was hyperintense on T2-weighted images and was enhanced after administration of contrast material. CT provided a larger spectrum of imaging features as a result of the presence of both hyperattenuating areas (caused by retention of iodized oil) and hypoattenuating areas (due to ethanol-induced necrosis).
CT and MR imaging findings proved useful in the evaluation of the response of HCC to combined TAE and PEI.
探讨计算机断层扫描（CT）和磁共振成像（MR）在评估肝细胞癌（HCC）经肝动脉化疗栓塞术（TAE）联合经皮乙醇注射（PEI）治疗反应中的可靠性。
1991年1月至1992年11月，20例（15例男性，5例女性，年龄53 - 73岁[平均64.6岁]）患有31个HCC病灶的患者在接受TAE和PEI联合治疗前后接受了CT和MR成像检查。
27个肿瘤在治疗后的T2加权图像和钆增强T1加权图像上呈低信号，活检显示为坏死。在4例不完全坏死的病例中，存活肿瘤在T2加权图像上呈高信号，注射对比剂后强化。由于存在高密度区（由碘化油滞留引起）和低密度区（由于乙醇诱导的坏死），CT提供了更广泛的成像特征。
CT和MR成像结果被证明有助于评估HCC对TAE和PEI联合治疗的反应。
