Lloyd C M, Walker A R
Centre for Tropical Veterinary Medicine, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, Royaume-Uni.
Rev Elev Med Vet Pays Trop. 1993;46(1-2):313-6.
The systemic effect of adult and nymphal Amblyomma variegatum on the pathogenesis of experimental infections of Dermatophilus congolensis was investigated. Three groups of four sheep were used with all 12 sheep being infected with identical titrated doses of D. congolensis One group of sheep was simultaneously infested with adult A. variegatum the second with nymphal A. variegatum and the third group were the controls, with no exposure to ticks. Assessment of the resulting infections indicate that the systemic effect of this tick is confined to the adults. Skin and serological tests using foreign antigens showed significantly reduced cell mediated and humoral immune response only in the sheep infested with adult A. variegatum.
研究了成年和若虫期杂色花蜱对刚果嗜皮菌实验性感染发病机制的全身影响。使用了三组四只绵羊，所有12只绵羊均感染相同滴定剂量的刚果嗜皮菌。一组绵羊同时感染成年杂色花蜱，第二组感染若虫期杂色花蜱，第三组为对照组，不接触蜱虫。对由此产生的感染进行评估表明，这种蜱的全身影响仅限于成年蜱。使用外来抗原进行的皮肤和血清学检测显示，仅在感染成年杂色花蜱的绵羊中，细胞介导免疫反应和体液免疫反应显著降低。
