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肾移植受者的内脏利什曼病:诊断和治疗问题

Visceral leishmaniasis in a renal transplant recipient: diagnostic and therapeutic problems.

作者信息

Sharma R K, Jha R, Kumar P, Kher V, Gupta A, Kumar A, Gulati S, Arora P, Murari M, Bhandari M

机构信息

Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

出版信息

Am J Nephrol. 1996;16(4):358-60. doi: 10.1159/000169024.

DOI:10.1159/000169024
PMID:8739293
Abstract

Visceral leishmaniasis is infrequently reported in renal transplant recipients. A 40-year-old renal transplant recipient developed hepatosplenomegaly and pyrexia of unknown origin 5 months after transplantation. Visceral leishmaniasis was confirmed on bone marrow examination. The usual dose of antiparasitic therapy with stibogluconate sodium failed to eradicate Leishmania donovani. High-dose conventional therapy with stibogluconate sodium for an extended period of time was successful in the treatment of a relapse of leishmaniasis.

摘要

内脏利什曼病在肾移植受者中鲜有报道。一名40岁的肾移植受者在移植后5个月出现肝脾肿大和不明原因发热。骨髓检查确诊为内脏利什曼病。常规剂量的葡萄糖酸锑钠抗寄生虫治疗未能根除杜氏利什曼原虫。大剂量葡萄糖酸锑钠常规治疗较长时间成功治愈了利什曼病复发。

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Solid Organ Transplant and Parasitic Diseases: A Review of the Clinical Cases in the Last Two Decades.实体器官移植与寄生虫病:过去二十年临床病例综述
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Cytomegalovirus and Leishmania donovani coinfection in a renal allograft recipient.
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Indian J Nephrol. 2011 Apr;21(2):128-31. doi: 10.4103/0971-4065.78064.
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Opportunistic infections (non-cytomegalovirus) in live related renal transplant recipients.活体亲属肾移植受者的机会性感染(非巨细胞病毒)
Indian J Urol. 2009 Apr;25(2):161-8. doi: 10.4103/0970-1591.39547.
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Transmission of tropical and geographically restricted infections during solid-organ transplantation.实体器官移植期间热带及地域局限性感染的传播
Clin Microbiol Rev. 2008 Jan;21(1):60-96. doi: 10.1128/CMR.00021-07.