Sun Z C
PLA 254 Hospital, Tianjin.
Zhonghua Fu Chan Ke Za Zhi. 1993 Dec;28(12):731-3, 760-1.
DNA index and cell cycle distribution were studied by flow cytometry in 32 cases of ovarian borderline cystadenoma, 16 ovarian cystadenocarcinoma and 12 ovarian benign cystadenoma, and their relations to pathological patterns of the diseases were inquired. The results showed that the DNA index and S+G2M phase in cell cycle of the diseases were related to their pathological patterns. The DNA index and S+G2M cell were increased by turn from benign to borderline and to malignant tumor. DNA index and cell cycle distribution might be valuable in reflecting the biological behavior of deteriorating ovarian cystadenoma. The authors consider that determination of DNA content and cell cycle could be biological indexes of supplementary diagnosis for the deterioration of borderline tumor.
采用流式细胞术对32例卵巢交界性囊腺瘤、16例卵巢囊腺癌和12例卵巢良性囊腺瘤进行DNA指数及细胞周期分布研究，并探讨其与疾病病理类型的关系。结果显示，这些疾病的DNA指数及细胞周期中的S + G2M期与其病理类型有关。DNA指数及S + G2M细胞从良性肿瘤到交界性肿瘤再到恶性肿瘤依次升高。DNA指数及细胞周期分布可能对反映卵巢囊腺瘤恶变的生物学行为有价值。作者认为，测定DNA含量及细胞周期可作为交界性肿瘤恶变辅助诊断的生物学指标。
