Kaplan S L, Simms R M, Busner J
Rockland Children's Psychiatric Center, New York State Office of Mental Health, Orangeburg 10962.
J Am Acad Child Adolesc Psychiatry. 1994 Jan;33(1):35-44. doi: 10.1097/00004583-199401000-00006.
This study was designed to assess outpatient child psychiatrists' prescribing practices.
Of 1,422 outpatients in two public, university affiliated settings in New York and Ohio, the charts of 146 medicated and 126 nonmedicated randomly selected patients were reviewed for demographic variables, DSM-III-R diagnoses, medications prescribed, and charted prescription rationales.
Fifteen percent of the 800 outpatients seen in a 1-month period in New York, and 19% of the 626 outpatients seen in a 1-year period in Ohio were prescribed medication. Patients medicated by clinic psychiatrists were significantly more likely than nonmedicated patients to be psychotic and to have been hospitalized previously, and significantly less likely to have adjustment disorder. Using standards employed by drug utilization review committees, medications were prescribed appropriately in approximately 90% of cases. Of concern, 65% of patients given antipsychotics in New York and 67% in Ohio were not psychotic; the primary target symptom in such cases was aggression.
Prescribing practices appeared to be appropriate, although the use of antipsychotic medications in nonpsychotic children is a concern for the field of child psychiatry. The strong similarity of practices in two independent and geographically remote sites suggests the findings are generalizable to providers in other public, university affiliated settings.
本研究旨在评估儿童精神科门诊医生的处方行为。
在纽约和俄亥俄州两所大学附属的公立机构中的1422名门诊患者里,随机抽取了146名接受药物治疗的患者和126名未接受药物治疗的患者的病历,以审查人口统计学变量、DSM-III-R诊断、所开药物及记录的处方理由。
在纽约1个月内就诊的800名门诊患者中,15%的患者被开具了药物;在俄亥俄州1年内就诊的626名门诊患者中,19%的患者被开具了药物。与未接受药物治疗的患者相比,由门诊精神科医生开具药物治疗的患者患精神病的可能性显著更高,且此前住院的可能性也显著更高,而患适应障碍的可能性显著更低。按照药物利用审查委员会采用的标准,约90%的病例药物处方是恰当的。令人担忧的是,在纽约接受抗精神病药物治疗的患者中有65%并非精神病患者,在俄亥俄州这一比例为67%;此类病例中的主要目标症状是攻击行为。
尽管在非精神病性儿童中使用抗精神病药物是儿童精神病学领域关注的问题,但处方行为似乎是恰当的。在两个独立且地理位置遥远的地点的行为具有很强的相似性,这表明研究结果可推广至其他大学附属公立机构的医疗服务提供者。