[Prophylactic effects of a long-term therapy with vitamin A in stress ulcer? (author's transl)].

The possibility of a protective effect on the development of stress ulcers by increased vitamin A supplements was investigated in albino rats. No differences were found between vitamin A treated and control animals as regards frequency and size of the induced ulcers. Neither did vitamin A pre-treatment lead to increased staining of PAS-positive substances in the gastric mucosa. Measured activity of lysosomal enzymes in the gastric secretion was significantly higher for chitobiase and acid phosphatase in animals pretreated with 10,000 IU of vitamin A than in control animals.