Tassé D P
Can J Surg. 1982 Mar;25(2):194-5.
The protective effect of vitamin A and diphenylhydantoin on restraint ulcers has been studied in 105 rats. The Sprague-Dawley female rats were divided into four groups. All were fasted for 24 hours, then restrained and fasted for another 24 hours. Control rats (receiving 1 ml of 0.9% saline solution) were compared with groups receiving either vitamin A, diphenylhydantoin, or both. Diphenylhydantoin significantly (P less than 0.001) protected the rats against ulcers. Vitamin A showed no protective effect and did not potentiate the effect of diphenylhydantoin.
已在105只大鼠中研究了维生素A和苯妥英对束缚性溃疡的保护作用。将斯普拉格-道利雌性大鼠分为四组。所有大鼠均禁食24小时，然后进行束缚并再禁食24小时。将对照大鼠（接受1毫升0.9%盐溶液）与接受维生素A、苯妥英或两者的组进行比较。苯妥英对大鼠溃疡有显著的保护作用（P小于0.001）。维生素A未显示出保护作用，也未增强苯妥英的作用。
