Stenager E, Knudsen L, Jensen K
Clinical Neuro-Psychiatric Research Unit, Odense University Hospital, Denmark.
Acta Neurol Belg. 1994;94(1):53-6.
In a cross-sectional study of 94 patients (42 males, 52 females) with definite multiple sclerosis (MS) in the age range 25-55 years, the correlation of neuropsychological tests with the ability to read TV-subtitles and with the use of sedatives is examined. A logistic regression analysis reveals a significant correlation between results of an attention and perceptual motor speed test i.e. Symbol Digit Modalities test and the ability to read TV-subtitles, but no correlation was found with another attention and perceptual motor speed test, or verbal or visual memory. No correlation between the use of sedatives and results on neuropsychological tests was found. Anxiety was not correlated with the ability to read TV-subtitles. It is concluded that visual deficits but not the use of sedatives may be a confounding factor in neuropsychological testing in MS.
在一项针对94例年龄在25至55岁之间确诊为多发性硬化症（MS）的患者（42名男性，52名女性）的横断面研究中，研究了神经心理学测试与阅读电视字幕能力以及镇静剂使用之间的相关性。逻辑回归分析显示，注意力和感知运动速度测试（即符号数字模态测试）的结果与阅读电视字幕的能力之间存在显著相关性，但与另一项注意力和感知运动速度测试、言语或视觉记忆之间未发现相关性。未发现镇静剂的使用与神经心理学测试结果之间存在相关性。焦虑与阅读电视字幕的能力无关。得出的结论是，视觉缺陷而非镇静剂的使用可能是MS神经心理学测试中的一个混杂因素。
