Plohmann A M, Kappos L, Ammann W, Thordai A, Wittwer A, Huber S, Bellaiche Y, Lechner-Scott J
Department of Neurology, University Hospital, Basel, Switzerland.
J Neurol Neurosurg Psychiatry. 1998 Apr;64(4):455-62. doi: 10.1136/jnnp.64.4.455.
To evaluate the efficacy of a computer based retraining of specific impairments of four different attentional domains in patients with multiple sclerosis.
Twenty two outpatients with multiple sclerosis received consecutively a specific training comprising 12 sessions in each of the two most impaired attention functions. The baseline of attentional deficits, the performance after each training period, and the course of performance in the next nine weeks was assessed by a computerised attention test battery. Additionally, the impact of the training on daily functioning was evaluated with a self rating inventory.
Subgroups of patients with multiple sclerosis showing different patterns of attentional impairment could be separated. Significant improvements of performance could almost exclusively be achieved by the specific training programmes. The increase of performance remained stable for at least nine weeks. For quality of life patients reported less attention related problems in everyday situations.
In patients with multiple sclerosis it seems worthwhile to assess attentional functions in detail and to train specific attention impairments selectively.
评估针对多发性硬化症患者四个不同注意力领域特定损伤的计算机辅助再训练的疗效。
22名多发性硬化症门诊患者连续接受针对两种受损最严重的注意力功能的特定训练，每种训练包含12节课程。通过计算机化注意力测试组评估注意力缺陷的基线、每个训练阶段后的表现以及接下来九周的表现过程。此外，用自评量表评估训练对日常功能的影响。
可区分出表现出不同注意力损伤模式的多发性硬化症患者亚组。几乎只有通过特定训练计划才能实现表现的显著改善。表现的提升至少在九周内保持稳定。患者报告在日常生活中与注意力相关的问题减少，生活质量提高。
对于多发性硬化症患者，详细评估注意力功能并选择性地训练特定的注意力损伤似乎是值得的。
