Hobman T C
Division of Cellular and Molecular Medicine, University of California, San Diego, La Jolla 92093-0651.
Trends Microbiol. 1993 Jul;1(4):124-30. doi: 10.1016/0966-842x(93)90126-c.
Certain enveloped viruses are known to assemble on membranes of the Golgi complex. Intracellular budding is facilitated by targeting of the viral glycoproteins to this organelle. It is likely that these viral glycoproteins are retained in the Golgi by the same means as are endogenous Golgi proteins. Consequently, the study of Golgi-specific viral proteins has provided important clues to the nature of Golgi retention signals.
已知某些包膜病毒会在高尔基体复合体的膜上组装。病毒糖蛋白靶向该细胞器有助于在细胞内出芽。这些病毒糖蛋白很可能通过与内源性高尔基体蛋白相同的方式保留在高尔基体中。因此，对高尔基体特异性病毒蛋白的研究为高尔基体保留信号的性质提供了重要线索。
