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糖尿病肾病(作者译)

[Diabetic nephropathy (author's transl)].

作者信息

Mertz D P

出版信息

MMW Munch Med Wochenschr. 1976 Jan 30;118(5):123-8.

PMID:814441
Abstract

The term diabetic nephropathy includes the Kimmelstiel-Wilson intercapillary glumerulosclerosis (1936), arterio-arteriolosclerotic changes and pyelonephritis. In principle, diabetic nephropathy becomes more frequent with increasing duration of diabetes mellituus. Pyelonephritis is 4 to 5 times more frequent in diabetics than in the general population. Elderly overweight women are particularly at risk. - Only the nodular intercapillary glomerulosclerosis and not the diffuse or exudative form is specific for diabetes mellitus. It is found in 20-40% of all diabetics who have had the disease for 10-15 years. Whether the microangiopathy is typical of diabetes mellitus remains to be seen. Due to the intense cardiovascular changes, possible disorders of brain and liver function and infection, the prognosis of renal insufficiency is considerably worse in diabetics than in non-diabetics.

摘要

糖尿病肾病这一术语包括金梅尔施泰因-威尔逊氏毛细血管间肾小球硬化症(1936年)、小动脉-小动脉硬化性改变和肾盂肾炎。原则上,糖尿病肾病的发病率会随着糖尿病病程的延长而增加。糖尿病患者患肾盂肾炎的几率是普通人群的4至5倍。老年超重女性尤其危险。——只有结节性毛细血管间肾小球硬化症,而非弥漫性或渗出性形式,是糖尿病所特有的。在患糖尿病10至15年的所有糖尿病患者中,有20%至40%会出现这种病症。微血管病变是否为糖尿病所特有仍有待观察。由于严重的心血管变化、可能出现的脑和肝功能紊乱以及感染,糖尿病患者肾功能不全的预后比非糖尿病患者要差得多。

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