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广宿主范围温和型链霉菌噬菌体phi HAU3的特性及噬菌粒的构建

Characterization of phi HAU3, a broad-host-range temperate streptomyces phage, and development of phasmids.

作者信息

Zhou X, Deng Z, Hopwood D A, Kieser T

机构信息

Department of Soil Sciences and Agrochemistry, Huazhong Agricultural University, Wuhan, Hubei, People's Republic of China.

出版信息

J Bacteriol. 1994 Apr;176(7):2096-9. doi: 10.1128/jb.176.7.2096-2099.1994.

DOI:10.1128/jb.176.7.2096-2099.1994
PMID:8144476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC205316/
Abstract

phi HAU3 is a temperate Streptomyces phage with cohesive ends and a broad host range that includes Streptomyces hygroscopicus 10-22, a producer of antifungal compounds, but it fails to grow on Streptomyces lividans 66. Two phasmid derivatives were constructed that function as lambda cosmid vectors in Escherichia coli and as phages in Streptomyces spp.

摘要

phi HAU3是一种具有粘性末端和广泛宿主范围的温和型链霉菌噬菌体，其宿主范围包括产抗真菌化合物的吸水链霉菌10-22，但不能在变铅青链霉菌66上生长。构建了两种噬菌粒衍生物，它们在大肠杆菌中作为λ粘粒载体起作用，在链霉菌属中作为噬菌体起作用。

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本文引用的文献

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Physical map of the Streptomyces lividans 66 genome and comparison with that of the related strain Streptomyces coelicolor A3(2).淡紫灰链霉菌66基因组的物理图谱及其与相关菌株天蓝色链霉菌A3(2)基因组的比较。
J Bacteriol. 1993 Jun;175(11):3422-9. doi: 10.1128/jb.175.11.3422-3429.1993.
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Development of a gene cloning system for Streptomyces hygroscopicus subsp. yingchengensis, a producer of three useful antifungal compounds, by elimination of three barriers to DNA transfer.通过消除DNA转移的三个障碍，开发一种用于吸水链霉菌应城亚种（三种有用抗真菌化合物的产生菌）的基因克隆系统。
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Isolation and characterization of Micromonospora phage PhiHAU8 and development into a phasmid.微小单孢菌噬菌体PhiHAU8的分离、特性鉴定及构建成噬菌粒
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Physical analysis of antibiotic-resistance genes from Streptomyces and their use in vector construction.链霉菌抗生素抗性基因的物理分析及其在载体构建中的应用。
Gene. 1982 Nov;20(1):51-62. doi: 10.1016/0378-1119(82)90086-5.
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Rapid and efficient cosmid cloning.快速高效的黏粒克隆
Nucleic Acids Res. 1981 Jul 10;9(13):2989-98. doi: 10.1093/nar/9.13.2989.
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Genetics and molecular biology of Streptomyces bacteriophages.链霉菌噬菌体的遗传学与分子生物学
Microbiol Rev. 1980 Jun;44(2):206-29. doi: 10.1128/mr.44.2.206-229.1980.
8
Streptomyces albus G mutants defective in the SalGI restriction-modification system.白色链霉菌G中SalGI限制修饰系统存在缺陷的突变体。
J Gen Microbiol. 1980 Feb;116(2):323-34. doi: 10.1099/00221287-116-2-323.
9
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Nucleic Acids Res. 1988 May 25;16(10):4341-52. doi: 10.1093/nar/16.10.4341.