Müller A E, Thiele H G
Immun Infekt. 1976 Feb;4(1):14-22.
Since the etiology of rheumatoid arthritis presently is mostly unknown, the therapeutical efforts are focussed on attempts to influence the pathogeneic events occurring in this disease. Among the discussed pathogenic mechanisms aberration of immunereactions seem to play an important role. The drugs mainly used for basical treatment of rheumatoid arthritis are cytostatics, D-penicillamine, gold salts and chloroquine. The clinical experiences with these drugs and their mode of action are reviewed.
由于目前类风湿性关节炎的病因大多未知，治疗工作主要集中在试图影响该疾病中发生的致病过程。在讨论的致病机制中，免疫反应异常似乎起着重要作用。类风湿性关节炎基础治疗主要使用的药物是细胞抑制剂、D-青霉胺、金盐和氯喹。本文综述了这些药物的临床经验及其作用方式。
