系统性红斑狼疮的免疫抑制药物治疗
Immunosuppressive drug therapy of systemic lupus erythematosus.
作者信息
Fox D A, McCune W J
机构信息
Division of Rheumatology, University of Michigan Medical Center, Ann Arbor.
出版信息
Rheum Dis Clin North Am. 1994 Feb;20(1):265-99.
PMID:8153402
Abstract
This article reviews the biologic effects of cyclophosphamide and azathioprine relevant to the treatment of systemic lupus erythematosus (SLE). Other agents used less commonly for SLE, such as methotrexate, chlorambucil, and cyclosporin-A, receive more limited attention. Clinical studies of efficacy and toxicity of these agents in their treatment of SLE are then described in detail.
摘要
本文综述了环磷酰胺和硫唑嘌呤与系统性红斑狼疮（SLE）治疗相关的生物学效应。其他较少用于SLE治疗的药物，如甲氨蝶呤、苯丁酸氮芥和环孢素A，则受到的关注较为有限。随后详细描述了这些药物治疗SLE的疗效和毒性的临床研究。
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