Cochrane A H, Aikawa M, Jeng M, Nussenzweig R S
J Immunol. 1976 Mar;116(3):859-67.
Immunization with irradiated sporozoites produces a considerable degree protection against rodent, simian, and human malaria. This protection is in part antibody mediated. Antibodies neutralize sporozoites (SNA), i.e. abolish their infectivity, and cause, in vitro, the formation of a thread-like precipitate on the parasites (CSP reaction). The present study was undertaken to characterize the ultrastructural aspects of antibody-sporozoite interaction.
用辐照子孢子进行免疫可对啮齿动物、灵长类动物和人类疟疾产生相当程度的保护作用。这种保护作用部分是由抗体介导的。抗体可中和子孢子（SNA），即消除其感染性，并在体外使寄生虫上形成线状沉淀物（CSP反应）。本研究旨在描述抗体与子孢子相互作用的超微结构特征。
